The Ova Ressources biological resource centre (CRB OvaRessources) manages the collection of biological samples at the Centre François Baclesse associated with ovarian cancer.
- Head of department: Dr Cécile Blanc-Fournier
- Medical management: Dr Cécile Blanc-Fournier
- Scientific management: Laurent Poulain
- Operational engineer: Mélanie Briand (3/4 FTE)
- Quality engineer: Didier Bozonnet (1/2 FTE)
- Technician: Benoît Goudergues (1/2 FTE)
- Secretary: Séverine Ricci (1/4 FTE)
The research work developed by the BioTICLA laboratory, within the Inserm ANTICIPE unit, aims at improving therapeutic management of ovarian cancers (as per the Centre François Baclesse’s medical and scientific project). It concerns the different levels and aspects of such management, such as the definition of predictive factors, the identification of new therapeutic targets and the preclinical validation of adapted therapeutic tools.
Within this context, a collection of tumoral, ascitic, seric and urinary samples, appropriately annotated in terms of their clinico-pathological parameters, has been compiled, in order to enable correlation between the chemosensitivity profile (conventional or innovative) and studied biomarkers (tumoral or circulating).
Samples collected since the year 2000, together with a vast range of associated clinico-biological data, now constitute a high added value collection for clinicians and researchers working in the field of onco-gynaecology. All these samples collectively comprise the CFB’s ‘OvaRessources’ biological resource centre.
The CRB OvaRessources’ mission includes:
- organising the collection of biological samples associated with ovarian cancer, in coordination with the CFB’s care, biopathology and clinical research departments.
- guaranteeing patient consent and sample annotation
- guaranteeing quality in terms of sampling, and conservation up to release from the CRB
CRB OvaRessources is NF S 96-900 certified since 2016.
With regards to the management of sampling and sample conservation, the CRB OvaRessources uses, in particular, equipment made available by the Inserm ANTICIPE unit, the department of biopathology and the Caen Lower Normandy Tumour Bank.
Hence, samples can be used to obtain a range of specimens (supernatants of biological liquids, tumour slices, dissociated cells) conserved in different forms (fixed, culture, cryopreserved) and at different temperatures (room temperature, -20°C, -80°C and -150°C).