The Center for Microscopy Applied to Biology (CMAbio3)
Contact
The team
- Department Head: Pr Jean-Christiophe AVICE
- Administrative managers:
- Guénaelle LEVALLET (Histology platform),
- Benoît PLANCOULAINE (Quantitative Histoimaging Platform),
- Jean-Christophe AVICE (Microscopy).
- Technical managers :
- Maëlle GUYOT (Histology platform),
- Nicolas ELIE (Quantitative Histoimaging Platform),
- Didier GOUX (Microscopy).
Activities
The Centre de Microscopie Appliquée à la Biologie (CMAbio3) platform comprises three technical platforms:
- A histology platform specialized in the preparation, staining and immunostaining of biological samples.
This platform is located in the Histology Laboratory at Caen University Hospital,
- A microscopy platform dedicated to the preparation of biological samples for electron microscopy.
Observations can be made at tissue, cellular and sub-cellular levels using photonic and electron microscopy. Created in 1968, this facility is located on Campus 1,
- A quantitative histo-imaging platform - a unique feature of CMABio3, as it specializes in image processing and analysis.
This platform is located in the Centre François Baclesse (Research Building) and on Campus 1.
Thanks to the combined expertise of the three technical platforms, CMAbio3 now offers a range of complementary services, providing technical support from the collection of samples (cells/tissues), their preparation/packaging, staining, morphological or immunochemical analysis, observation (at various resolutions), right through to computerized image analysis.
The 6 staff (3 permanent) of CMABio3 work in synergy to fulfill their missions of service, advice and training for students, technicians, researchers from the University or external users, in all techniques of preparation, observation of samples and processing/analysis of the images obtained. This synergy enables CMAbio3 to bring high added value to research projects involving microscopy in biology.
Technical resources
CMABio3 is equipped to prepare, observe and analyze the biological samples entrusted to it. Among this list of equipment, CMABio3 has the following:
- Axozoom
- Cryo-ultramicrotome
- Confocal laser scanning microscope
- Scanning electron microscope
- Transmission electron microscope
- Ultramicrotome
- Vibratome
- Kerosene coating station,
- Dako Cryostat
- Routine or special coloring machines
- Immunohistochemistry (IHC)
- Fluorescent in situ hybridization (FISH)
- LASER micro-dissector
- Olympus VS120 slide scanner for white light, polarized light and fluorescence scanning.
- Aperio CS slide scanners, Computer workstations.
Partners
At regional level :
- Regional projects with Rouen and Caen research units
Internationally :
- Inter-Reg projects and collaborations with European units